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Planning, design and requirements for biological laboratories

The formulation of the process design task book of modern biological laboratory includes the development of the regional and functional requirements of each department of laboratory building and each laboratory; The architecture, decoration contents, door and window requirements, environmental control and electricity consumption of each room in the biological laboratory (lighting, communication and network, gas pipelines, air conditioning, drainage, fire protection, structure and other process design requirements); Develop a list of fixed laboratory equipment required for each biology laboratory. The construction plan of aseptic laboratory - clean laboratory - biosafety laboratory includes: building layout and decoration, air conditioning, water supply and drainage, gas supply, electrical design, centralized control, security, construction technology, testing, training and other aspects. Laboratory furniture air conditioning system is the key to the safe operation of clean laboratory-biosafety laboratory. Since the operating object of clean laboratory-biosafety laboratory is a dangerous microorganism, which is harmful to human body, animals and plants or the environment, it is necessary to maintain the relative negative pressure environment of clean laboratory-biosafety laboratory at any time by using a reasonable air conditioning system, so as to ensure that dangerous microorganisms in the laboratory cannot spread to the external environment.


The process design/equipment planning of a modern biological laboratory includes the planning of fixed equipment, process layout, expanded process plan, main elevation and main section of a typical biological laboratory, and fixed biological laboratory in accordance with the requirements of international standards. International biological Laboratory Standards and Project process Assignment. The data and engineering design of spare parts manufacturers are summarized. Specifically, modern biological laboratory building process design requirements are as follows:


1. Base environment


Based on the analysis of the current situation of the site, the design concept of building as the environmental background is adopted to integrate a single building into the environment.


2. Architectural aspects


It mainly includes biological laboratory architectural design, interior decoration material requirements, etc. In order to ensure the safe operation of biomedical research, the basic work area size (ELM) of a laboratory is the size of the work area required to plan it. Laboratory ELM typically includes length requirements for operating stations, laboratory equipment (including lockers), workstations, chemical exhaust hoods, and biosafety cabinets.


Current laboratory design trends have begun to move towards the spatial dimension of the planned area, rather than just the length of the planned area. This trend is due to the adoption of modular laboratory formats.


Since the building area includes the circulation area, the building core area, the wall area and the public area, in general, it must be greater than the use area of the specific functional area. The basic conversion factor for laboratory area (including internal circulation and functional allocation area) is between 1.7 and 2.2, according to the AIA's conversion method for use area and building area. When actually planning the total area of the converted project, adjustments need to be made accordingly.


Laboratory building materials should be durable, easy to clean, and should contribute to creating a comfortable and safe working environment. Key factors in material design are ease of cleaning, ease of maintenance, ease of storage and reduced toxic reproduction. The selection of materials for wall penetration and floor treatment must also take into account the safety of laboratory personnel.


3. Structure


Including biological laboratory structure design, structural load requirements. Because vibration can interfere with sensitive laboratory instruments, designers must consider proper vibration control, placing vibration sources in areas away from sensitive instruments, and conducting a detailed analysis of the vibration response of the building structure. In order to control the propagation of vibrations in the laboratory area, engineers need to consider a number of structural factors in the early stages of design.


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