P3 laboratory is a biosafety protection Level 3 laboratory, abbreviated P is an abbreviation of English protect protection. The whole laboratory is completely sealed, and the indoor is in a state of negative pressure, so that the gas inside the laboratory will not leak outside and cause pollution.

According to the equipment and technical conditions, the biological laboratory is also divided into four levels (generally known as P1, P2, P3, P4 laboratories), level 1 is the lowest, level 4 is the highest. The laboratory is suitable for pathogenic microorganisms or their toxins that cause serious or even fatal diseases to humans mainly through the respiratory route; Such as SARS virus, Bacillus anthracis, Yersinia pestis, Mycobacterium tuberculosis, rabies virus and other highly pathogenic viruses.

Significance of P3 laboratory in virus research:

1) Effectively protect the environment from pollution and ensure the safety of people's lives;

2) Effectively protect the operator from infection; 3) Effectively protect pathogen samples from contamination; What is special about P3 biological laboratory:

P3 laboratory is the national three-level security protection laboratory, emphasizing the protection of the virus, and the ordinary laboratory is different, here is tightly guarded, with multiple checkpoints, people in and out have to be fully armed, because P3 laboratory in which the study is often pathogenic microorganisms or their toxins, in addition to H7N9, and we are familiar with HIV HIV and so on. The whole laboratory is completely sealed, and the indoor is in a state of negative pressure, so that the gas inside the laboratory will not run outside and cause pollution. In addition, there is a very strict process to enter the P3, which requires passing a medical examination, vaccination, and relevant technical knowledge examination before obtaining a license.

To establish a biosafety Level III laboratory, three conditions must be met:

First, there should be strict laboratory operation and technical procedures: laboratory personnel should be required to be professionally trained in dealing with pathogenic and potentially lethal pathogens, and supervised by qualified scientific workers who have experience in pathogen work. Laboratory personnel must wear isolation clothing when working, and all steps related to operations such as biological pathogens should be carried out in a biosafety cabinet or other physical containment device.

The second is to install a first-level barrier: the so-called first-level barrier mainly refers to safety equipment, including a series of biosafety cabinets, various closed containers and other engineering control facilities designed to eliminate or reduce exposure to harmful biological materials.

Third, the design of laboratory buildings should meet the standards of secondary barriers: mainly used to prevent infectious microorganisms from escaping into the environment, to avoid the exposure of workers and the environment in adjacent areas to possible infectious aerosols.